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How is methotrexate dispensed? Dosing. When methotrexate is used for rheumatoid arthritis, it is taken either once a week or in three divided doses over 36 hours once a week. Specify on every prescription, and the dispensed medicine label, the day of the week (written in full) the dose is to be taken.
How long can a person take methotrexate? How long can a patient stay on Methotrexate ? Many patients with rheumatoid arthritis have stayed on this drug for 20 years or more.
How do you take methotrexate tablets? Most arthritis patients take methotrexate orally, in a dose consisting of several pills. Some find that splitting the dose eases GI side effects; take half the pills in the morning and the other half 12 hours later, preferably with food. Ask about medication.
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