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Is there an alternative to methotrexate? In elderly patients with RA who are unable to tolerate methotrexate, the alternatives are hydroxychloroquine or sulfasalazine for mild-to-moderate disease and cyclosporin or leflunomide for severe disease, given in combination with low-dose oral corticosteroids.
Can you get pregnant on methotrexate? Methotrexate isn't safe during pregnancy Using methotrexate while you 're pregnant could end your pregnancy or cause severe birth defects. These birth defects could affect the way your child looks, develops, or functions for the rest of their life.
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