In addition to transporting oxygen throughout the body, the https://www.chinacaremedical.com/c/cell-counter-hematology-cbc-anal..." style="color: rgb(255, 0, 0); text-decoration: underline; hematologic system is responsible for the execution of the immune response against tumor cells and invading pathogens, as well as hemostasis (blood clotting). These functions are carried out by the blood cells erythrocytes (red blood cells), leukocytes (white blood cells), and thrombocytes (platelets), in the appropriate order. It is important to note that the function of all three cell types is influenced by circadian rhythms. In this review, we describe these oscillations, investigate their mechanistic underpinnings, and highlight the most important implications of their findings. The fact that erythrocytes are anucleate confirms the existence of a nontranscriptional circadian clock by the presence of circadian rhythms in these cells. Specifically, leukocyte rhythms may be responsible for daily variations in the severity of allergic reactions, the symptoms of chronic inflammatory diseases, and the body's response to infection, whereas the rhythmic properties of thrombocytes may be responsible for daily variations in the incidence of heart attack and stroke. As a result, the efficacy of treatments for these conditions is likely to be dependent on the time at which they are delivered. Last but not least, we present preliminary evidence that disruption of the circadian rhythm in the hematologic system may contribute to the negative effects of poor diet, shift work, and alcohol consumption on human health.Circadian rhythms are endogenous 24-hour oscillations in physiology and behavior that allow an organism to anticipate and adapt to the changing temporal demands of the environment (Johnson et al., 2004). Circadian rhythms are a type of circadian rhythm that is found in all living things. The term circadian is derived from the Latin words circa, which means "approximately," and diem, which means "day," which mean "approximately."It is possible that the sleep/wake cycle is the most obvious example of a circadian rhythm. Other examples include changes in locomotor activity, core body temperature, heart rate, blood pressure, hepatic metabolism, and hormone secretion on a daily basis (Hastings et al., 2008), among other things. However, until recently, little attention had been paid to circadian rhythms in the https://www.chinacaremedical.com/c/cell-counter-hematology-cbc-anal..." style="white-space: normal; color: rgb(255, 0, 0); hematologic system despite the fact that the brain and various peripheral tissues have been extensively studied.The average adult's body contains approximately 4.5 liters of blood, which accounts for approximately 7% of the total body mass (Cameron et al., 1999), according to Cameron et al. According to Waugh and Grant (2010), plasma accounts for 55% of total blood volume, with blood cells accounting for the remaining 45%. There are three different types of blood cells, each of which performs a different function. In addition to transporting oxygen from the lungs to body tissues, leukocytes (white blood cells) coordinate and carry out the immune response against tumor cells and invading pathogens, and thrombocytes (platelets) are required for hemostasis (blood clotting), which helps to prevent blood loss in the event of blood vessel damage (Waugh et al., 2010).