The US public and even some health experts may have underestimated the Covid-19 vaccine made by Janssen, a division of Johnson & Johnson, new data shows. And there's emerging evidence that it could still play an important role ahead.

A study published Thursday in the medical journal JAMA Network Open found that the J&J vaccine remains durable and effective, even through the surge of cases caused by the Delta variant. It was 76% effective overall in preventing Covid-19 infections and 81% effective in preventing Covid-related hospitalizations. The study also showed that it provided lasting immunity at least six months after the shots.
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Pfizer/BioNTech seek FDA authorization for fourth Covid-19 vaccine doses for people 65 and up
Pfizer/BioNTech seek FDA authorization for fourth Covid-19 vaccine doses for people 65 and up
And a CNN analysis of information collected by the US Centers for Disease Control and Prevention showed the J&J vaccine had the lowest breakthrough infection rate of all the vaccines since the week ending December 25, the latest five weeks of available data.
In January, during the Omicron surge, breakthrough infections were highest among those who received the Pfizer/BioNTech vaccine, followed by those who got Moderna. Those vaccinated with the Johnson & Johnson shot had the lowest incidence of breakthrough infections.
As of the week ending January 22, there were 650 infections per 100,000 people with the J&J vaccine. With Moderna, there were 757 per 100,000, and with Pfizer, the rate was 862 per 100,000.
Unvaccinated people were particularly vulnerable to getting sick during the Omicron and Delta surges, just as they were with the original version of the coronavirus. They were 3.2 times as likely to get sick as people who had the J&J vaccine. The unvaccinated were 2.8 times as likely to become infected than those who got Moderna and 2.4 times as likely as those who got Pfizer.