Meso Scale Discovery Biomarker Assays (MSD-ECL) is one of the most recent biomarker discovery methods that pharmaceutical companies use to assess the efficacy of new drugs. MSD-ECL combines two separate biochemistry pathways that allow the body to sense levels of an extracellular ligand, which is often proteins.

First, msd mesoscale immunogenicity assay measures the relative…

Biomarkers play an important role in disease identification and have now gained a more comprehensive role in drug discovery and development. The primary function of a biomarker in drug development is to facilitate early and robust drug efficacy and safety measurements. For a biomarker to take its rightful place in drug discovery and development, bioanalytical companies should focus on understanding disease mechanisms and therapeutic intervention, along with biomarker study validation and…

Outsourcing is the new modus operandi of the pharmaceutical industry. A large number of labs and Contract Research Organizations have sprung up to handle various requirements of the industry. Like any other niche, these companies vary in size.

Some CROs are behemoths with revenues in the billions and operations in several countries. Smaller CROs don’t match these numbers but continue to offer excellent services. At first glance, this seems like a David vs. Goliath scenario but…

As biotherapeutics grow and gain increasing importance, great opportunities arise for pharmaceutical development and human health. These large molecule (LM) drugs are poised to offer some revolutionary treatment options. As with conventional pharmaceutical development, the bioanalytical method continues to play a big role here as well.

And therein lies the challenge of large molecule bioanalysis. It has to contend with small molecule drugs. While that isn’t the problem by itself, the…