Circular dichroism spectrometers are widely used to study biomolecules such as proteins, DNA, and their conjugates in order to understand their secondary structure, chirality, and the impact of various factors such as temperature, pH, and solvent on their chirality. Demand for CD spectrometers is expected to rise as pharmaceutical and biopharmaceutical companies shift their focus from chemical formulations to biological drugs. Newly introduced CD modalities, such as FDCD, stopped-flow, vibrational CD, and so on, are broadening the application areas of CD spectrometers, and their adoption is expected to increase in the near future. Researchers from the public and private sectors are working together to create reference data for the circular dichroism of various biomolecules, which is expected to entice new researchers to use CD spectroscopy as a preferred analytical tool. The two major reference data sources for circular dichroism are DichroWeb and the Protein Circular Dichroism Data Bank (PCDDB). Although there has been an increase in awareness of the benefits of circular dichroism (CD) spectrometers, it is highly likely that the high cost of this medical equipment will provide an impetus to growth during the assessment period. Circular dichroism CD spectrometer sales may decline as a result of technological advancement.
Read More…