Narcotic analgesic combination drugs are medicines that contain an opiate pain reliever, with at least one different analgesic such as acetaminophen or ibuprofen. These should be utilized to treat direct to extreme pain when other less intense analgesics are not effective. Narcotic analgesics (also called sedatives, opioid analgesics, or opiates) ease intense and chronic extreme pain by binding to opioid receptors.

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The three types of opioid receptors are mu, delta, and kappa. Most opiate analgesics combination bind to the narcotic “mu” receptor and are extremely effective in relieving pain. However, these also initiate remunerate pathways implying that narcotic analgesic combination tends to cause dependence and addiction (where expanding doses are expected to give a similar pain-relieving effect). Diverse opiate pain relieving mixes have distinctive potencies and reactions in view of the ingredients these contain.

Rise in prevalence of osteoarthritis, back pain, and rheumatoid arthritis are the major factors propelling the global narcotic analgesic combination drugs market. Increase in incidence of overactive bladder also drives the narcotic analgesic combination drugs market. However, side effects of drugs such as constipation, vomiting, loss of appetite, and urination problem, and death due to overdose of narcotic analgesic combination drugs are factors likely to restrain the market in the next few years.

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Based on indication, the global narcotic analgesic combination drugs market can be segmented into chronic cough, osteoarthritis, rheumatoid arthritis, and others. The osteoarthritis segment is likely to expand at a rapid pace during the forecast period. This can be attributed to rise in geriatric population with osteoarthritis. In terms of drug class, the global Narcotic Analgesic Combination Drugs market can be categorized into opiate agonists, analgesics, and others. The analgesics segment is likely to expand at a rapid pace during the forecast period, attributed to high preference by doctors to relieve pain, as it has low side effects and help prevent blood clots in elderly patients.

Based on route of administration, the global narcotic analgesic combination drugs market can be classified into oral, intravenous, and intramuscular. The oral segment is likely to expand at a rapid pace during the forecast period.

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Oral administration is the most frequently preferred route by doctors because of its simplicity and convenience. Moreover, the degree of bioavailability of oral dose form of narcotic analgesic combination drugs is high and for this reason it quickly absorbed in the blood, only a tract amount remain in the gastrointestinal tract.

In terms of region, the global narcotic analgesic combination drugs market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. Growth of the narcotic analgesic combination drugs market in North America is attributed to favorable reimbursement policies for prescription drugs. Rise in geriatric population with osteoarthritis pain and availability of wide range of over-the-counter drugs for pain management are likely to propel the narcotic analgesic combination drugs market in Europe.

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Increase in geriatric population and rising awareness among the health professionals to address different diseases and infection through various combination drugs are anticipated to drive the market in Asia Pacific. Rise in prevalence of neuropathic pain, arthritic pain, and chronic back pain in Africa is expected to propel the narcotic analgesic combination drugs market in Middle East & Africa during the forecast period.

Key players operating in the global narcotic analgesic combination drugs market are BioDelivery Sciences International, Inc., Pfizer Inc., Allergan plc, Teva Pharmaceuticals, Akron, Inc., UCB, Inc., and Endo Pharmaceuticals, Inc., among others.

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