Ethanol is used in the management of toxicity due to ingestion of methanol, or ethylene glycol.
Ethanol is available under the following different brand and other names: alcohol (ethyl).
DOSAGES OF Ethanol
Adult and Pediatric Dosage Forms and Ethanol Strengths
Ethanol Injection solution (95%)
1 mL
5 mL
Dosage Considerations – Should be Given as Follows:
Methanol Toxicity,
Ethanol Poisoning (Off-label)
Adult
Loading dose
600 mg/kg intravenous (IV) (i.e., 7.6 mL/kg of 10% EtOH solution)
600-700 mg/kg oral/nasogastric (NG) using a 95% solution diluted to 20% or less with water or juice
Maintenance dose
65-155 mg/kg/hour depending on alcohol consumption status (lower for nondrinker)
Oral maintenance = 0.15 mL/kg/hour (IV = 1.4 mL/kg/hour) 10% Ethanol
Chronic alcoholics and hemodialysis patients need increased dose; increased maintenance by 50%; non-users may need less
Maintain serum Ethanol of 100-150 mg/dL [21.7-32.55 mmol/L]
Pediatric
Reduce Ethanol loading dose if methanol or ethylene glycol ingested with alcohol
May need to increase Ethanol maintenance dose in patients with chronic alcohol consumption
Loading dose (oral)
95% EtOH: 0.8-1 mL/kg
40% EtOH (80 proof undiluted liquor): 2 mL/kg
43% EtOH (86 proof undiluted liquor): 1.8 mL/kg
Maintenance dose (oral)
43% EtOH: 0.1 mL/kg/hour
95% EtOH: 0.1 mL/kg/hour
Intravenous (IV) dose (10% EtOH)
10% EtOH = 7.9 g/dL
Loading: 8-10 mL/kg IV; not to exceed 200 mL
Maintenance: 0.83 mL/kg/hour intravenous (IV)
10% EtOH = 7.9 g/dL
40% EtOH (80 proof undiluted liquor) = 31.6 g/dL
43% EtOH (86% proof undiluted liquor) = 34 g/dL
95% EtOH (absolute alcohol) = 75 g/dL
Continue maintenance dose until methanol or ethylene glycol levels are below 10 mg/dL
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